Question: Can CEA Levels Go Up And Down?

What is normal CEA range?

Normal Results The normal range is 0 to 2.5 ng/mL (0 to 2.5 µg/L).

In smokers, slightly higher values may be considered normal (0 to 5 ng/mL, or 0 to 5 µg/L)..

How do you lower CEA levels?

Thus, we suggest that exercise for 2-3 days per week decreases the expression of CEA and improves body condition, without loading fatigue or stress, which may contribute to preventing cancer in the elderly women.

Can tumor markers go up and down?

Tumor markers are most often used to track how a patient’s cancer responds to treatment. If the level is going down, the treatment is working. If it goes up, the cancer may be growing.

What is considered a high CEA level?

Levels of CEA higher than 20 ng/mL are considered very high. If you have CEA levels this high and you also have symptoms of cancer, it strongly suggests the cancer has not been removed successfully after treatment.

Does CEA increase with age?

Background. Carcinoembryonic antigen (CEA), a serological marker of malignant tumors, demonstrates a modest increase under nonmalignant conditions such as aging and smoking. Also, recent study results suggested that serum CEA levels may be related to insulin resistance or low-grade inflammation.

What can raise CEA levels?

A high level of CEA can be a sign of certain types of cancers. These include cancers of the colon and rectum, prostate, ovary, lung, thyroid, or liver. High CEA levels may also be a sign of some noncancerous conditions, such as cirrhosis, noncancerous breast disease, and emphysema.

What can cause a false positive CEA?

Elevated serum CEA is not highly specific for colon cancer recurrence, while various other gastrointestinal disorders such as pancreatitis, peptic ulcer disease, biliary tract abnormalities (benign or malignant) and liver disorders may contribute to increased serum CEA and false-positive results [2].

How reliable is a CEA blood test?

Doctors don’t use the CEA test to make a first-time diagnosis of cancer. This test isn’t an accurate way to screen for it because many other diseases can cause the levels of this protein to rise. And some people with cancer don’t have high CEA levels.

How accurate is a CEA blood test?

Sensitivity of CEA ranged from 17.4 % to 100 %, specificity ranged from 66.1 % to 98.4 %, positive predictive value ranged from 45.8 % to 95.2% and negative predictive value ranged from 74.5 % to 100 %.

Why does CEA go up and down?

The most frequent cancer which causes an increased CEA is cancer of the colon and rectum. Benign conditions which can elevate CEA include smoking, infections, inflammatory bowel disease, pancreatitis, cirrhosis of the liver, and some benign tumors in the same organs in which an elevated CEA level indicates cancer.

Can alcohol affect CEA levels?

The mean plasma carcinoembryonic antigen (CEA) level was found to be significantly increased in 66 patients with alcoholic liver disease (4.4μg/1) compared with the mean CEA level in 164 healthy blood donors (1.6μg/1, p < 0.001).

Is it normal for CEA levels to fluctuate?

Serum CEA levels fluctuate over time in healthy individuals, and the intraindividual variation has been reported to be about 30% [19].